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The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae

The effects of LPS on BBB integrity have been largely covered in a previous section, since LPS is a major model of systemic inflammation

This condition, called hypochlorhydria or achlorhydria when severe, impairs b12 absorption even without medication effects

AD is characterized by a progressive reduction in the num ber and maturation of adult neurons in the dentate gyrus (DG) of the hippocampus (Moreno-Jimenez et al., 2019), suggesting an impairment in hippocampal neurogenesis that is closely correlated with the loss of hippocampal functions and cognitive decline (Hollands et al., 2017